Publications

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Kumar S, Dietrich N, Kornfeld K. Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span. PLoS Genet. 2016 Feb 26;12(2):e1005866. doi: 10.1371/journal.pgen.1005866. eCollection 2016. PMID: 26918946

Warnhoff K, Kornfeld K. New links between protein N-terminal acetylation, dauer diapause, and the insulin/IGF-1 signaling pathway in Caenorhabditis elegans. Worm. 2015 Mar 11;4(2):e1023498. doi: 10.1080/21624054.2015.1023498. PMID: 26435887

Leight ER, Murphy JT, Fantz DA, Pepin D, Schneider DL, Ratliff TM, Mohammad DH, Herman MA, Kornfeld K. Conversion of the LIN-1 ETS Protein of Caenorhabditis elegans from a SUMOylated Transcriptional Repressor to a Phosphorylated Transcriptional Activator.
Genetics. 2015 Mar;199(3):761-75. doi: 10.1534/genetics.114.172668. Epub 2015 Jan 7.
PMID: 25567989

Roh HC, Dimitrov I, Deshmukh K, Zhao G, Warnhoff K, Cabrera D, Tsai W, Kornfeld K.
 A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans. Nucleic Acids Res. 2015 Jan;43(2):803-16. doi: 10.1093/nar/gku1360. Epub 2014 Dec 30. PMID: 25552416

Kumar S, Kocsisova Z, Kornfeld K. Keep on laying eggs Mama, RNAi my reproductive aging blues away. PLoS Genet. 2014 Dec 4;10(12):e1004808. doi: 10.1371/journal.pgen.1004808. eCollection 2014 Dec. PMID: 25474201

Warnhoff K, Murphy JT, Kumar S, Schneider DL, Peterson M, Hsu S, Guthrie J, Robertson JD, Kornfeld K. The DAF-16 FOXO transcription factor regulates natc-1 to modulate stress resistance in Caenorhabditis elegans, linking insulin/IGF-1 signaling to protein N-terminal acetylation.
PLoS Genet. 2014 Oct 16;10(10):e1004703. doi: 10.1371/journal.pgen.1004703. eCollection 2014 Oct. PMID: 25330323

Pickett CL, Dietrich N, Chen J, Xiong C, Kornfeld K. Mated progeny production is a biomarker of aging in Caenorhabditis elegans. G3 (Bethesda). 2013 Dec 9;3(12):2219-32. doi: 10.1534/g3.113.008664. PMID: 24142929

Roh HC, Collier S, Deshmukh K, Guthrie J, Robertson JD, Kornfeld K.
 ttm-1 encodes CDF transporters that excrete zinc from intestinal cells of C. elegans and act in a parallel negative feedback circuit that promotes homeostasis. PLoS Genet. 2013 May;9(5):e1003522. doi: 10.1371/journal.pgen.1003522. Epub 2013 May 23. PMID: 23717214

Pickett CL, Kornfeld K. Age-related degeneration of the egg-laying system promotes matricidal hatching in Caenorhabditis elegans. Aging Cell. 2013 Aug;12(4):544-53. doi: 10.1111/acel.12079. Epub 2013 May 2. PMID: 23551912

Roh HC, Collier S, Guthrie J, Robertson JD, Kornfeld K. Lysosome-related organelles in intestinal cells are a zinc storage site in C. elegans. Cell Metab. 2012 Jan 4;15(1):88-99. doi: 10.1016/j.cmet.2011.12.003. PMID: 22225878

Hughes SE, Huang C, Kornfeld K. Identification of mutations that delay somatic or reproductive aging of Caenorhabditis elegans. Genetics. 2011 Sep;189(1):341-56. doi: 10.1534/genetics.111.130450. Epub 2011 Jul 12. PMID: 21750263

Murphy JT, Bruinsma JJ, Schneider DL, Collier S, Guthrie J, Chinwalla A, Robertson JD, Mardis ER, Kornfeld K. 2011. Histidine protects against zinc and nickel toxicity in Caenorhabditis elegans. PLoS Genet. 2011 Mar;7(3):e1002013. Epub 2011 Mar 24.

Liu Z, Schneider DL, Kornfeld K, Kopan R.2010. Simple copy number determination with reference query pyrosequencing (RQPS) .Cold Spring Harb Protoc. 2010 Sep 1;2010(9):pdb.prot5491. doi: 10.1101/pdb.prot5491.

Johnson, K.G., Kornfeld, K. 2010. The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation. Dev. Biol. doi:10.1016/j.ydbio.2010.03.003. (Abstract)

Davis, D. E., Roh, H. C., Deshmukh, K., Bruinsma, J. J., Schneider, D. L., Guthrie, J., Robertson, J. D.,and Kornfeld, K. 2009. The Cation Diffusion Facilitator Gene cdf-2 Mediates Zinc Metabolism in Caenorhabditis elegans. Genetics. 182, 1015-33. (Abstract)

Collins, J.J., Evason, K., Pickett, C.L., Schneider, D.L., and Kornfeld, K. 2008. The Anticonvulsant Ethosuximide Disrupts Sensory Function to Extend C. elegans Lifespan. PLoS Genetics, 4(10):e1000230. (Abstract)

Bruinsma, J.J., Schneider D., Davis, D., and K. Kornfeld. 2008. Identification of mutations in Caenorhabditis elegans that cause resistance to high levels of dietary zinc and analysis using a genome-wide map of single-nucleotide polymorphisms scored by pyrosequencing. Genetics, 179: 811-828. (Abstract)

Evason, K., Collins, J.J., Huang, C., Hughes, S., and K. Kornfeld. 2008. Valproic acid extends C. elegans
lifespan
. Aging Cell, 7: 305-317. (Abstract)

Collins, J.J., C. Huang, S. Hughes and K. Kornfeld. 2007. The measurement and analysis of age-related
changes in Caenorhabditis elegans
. WormBook, ed. The C. elegans Research Community, WormBook, http://www.wormbook.org. (Abstract)

Hughes, S., K. Evason, C. Xiong and K. Kornfeld. 2007. Genetic and pharmacological factors that
influence reproductive aging in nematodes
. PLoS Genetics, 3(2): 254-265. (Abstract)

Collins, J.J., K. Evason and K. Kornfeld. 2006. Pharmacology of delayed aging and extended lifespan
of Caenorhabditis elegans
. Experimental Gerontology 41: 1032-1039. (Abstract)

Wagmaister, J. A., G.R. Miley, C.A. Morris, J.E. Gleason, L.M. Miller, K. Kornfeld and D. M.
Eisenmann. 2006. Identification of cis-regulatory elements from the C. elegans Hox gene lin-39 required for embryonic expression and for regulation by the transcription factors LIN-1, LIN-31, and LIN-39. Developmental Biology 297: 550-565. (Abstract)

Evason, K., and K. Kornfeld. 2006. Effects of anticonvulsant drugs on lifespan. Archives of Neurology, 63: 491-496. (Abstract)

Goldstein, J., D. Glossip, S. Nayak and K. Kornfeld. 2006. The CRAL/TRIO and GOLD domain protein CGR-1 promotes induction of vulval cell fates in Caenorhabditis elegans and interacts genetically with the Ras signaling pathway. Genetics, 172: 929-942. (Abstract)

Evason, K., C. Huang, I. Yamben, D.F. Covey and K. Kornfeld. 2005. Anticonvulsant medications extend worm life-span. Science 307: 258-262. (Abstract)

Leight, E., D. Glossip, and K. Kornfeld. 2005. Sumoylation of LIN-1 promotes transcriptional repression
and inhibition of vulval cell fates
. Development 132: 1047-1056. (Abstract)

Miley, G., D. Fantz, D. Glossip, X. Lu, R. Saito,, R. Palmer, T. Inoue, S. van den Heuvel, P. Sternberg,
and K. Kornfeld. 2004. Identification of residues of the Caenorhabditis elegans LIN-1 ETS domain
that are necessary for DNA binding and regulation of vulval cell fates
. Genetics 167: 1697-1709. (Abstract)

Huang, C., C. Xiong and K. Kornfeld. 2004. Measurements of age-related changes of physiological
processes that predict life span of Caenorhabditis elegan
s. Proc. Natl. Acad. Sci. USA., 101:
8084-8089. (Abstract)

Harding, A., V. Hsu, K. Kornfeld and J.F. Hancock. 2003. Identification of residues and domains of Raf important for function in vivo and in vitro. J. Biol. Chem. 278: 45519-45527. (Abstract)

Bruinsma, J. J., T. Jirakulaporn, A. J. Muslin and K. Kornfeld. 2002. Zinc ions and cation diffusion
facilitator proteins regulate Ras-mediated signaling
. Developmental Cell 2: 567-578. (Abstract)

Hsu, V., Zobel, C., Lambie, E., Schedl. T. and K. Kornfeld. 2002. Caenorhabditis elegans lin-45 raf is
essential for larval viability, fertility and the induction of vulval cell fates
. Genetics 160: 481-492. (Abstract)

Fantz, D.A., D. Jacobs, D. Glossip and K. Kornfeld. 2001. Docking sites on substrate proteins direct
extracellular-signal regulated kinase to phosphorylate specific residues
. J. Biol. Chem. 276:
27256-27265. (Abstract)

Jakubowski, J., and K. Kornfeld. 1999. A local, high-density, single-nucleotide polymorphism map used
to clone Caenorhabditis elegans cdf-1
. Genetics 153: 743-752. (Abstract)

Jacobs, D., D. Glossip, H. Xing, A.J. Muslin and K. Kornfeld. 1999. Multiple docking sites on substrate
proteins form a modular system that mediates recognition by ERK MAP kinase
. Genes & Development
13:163-175. (Abstract)

Jacobs, D., G.J. Beitel, S.G Clark. H.R. Horvitz and K. Kornfeld. 1998. Gain-of-function mutations in the
C. elegans lin-1 ETS gene identify a C-terminal regulatory domain phosphorylated by ERK MAP kinase
.
Genetics 149: 1809-1822. (Abstract)

Kornfeld, K. 1997. Vulval development in Caenorhabditis elegans. Trends in Genetics 13: 55-61. (Abstract)

Xing, H., K. Kornfeld and A.J. Muslin. 1997. The protein kinase KSR interacts with 14-3-3 protein and Raf.
Current Biology 7: 294-300. (Abstract)

Kornfeld, K., D.B. Hom and H.R. Horvitz. 1995. The ksr-1 gene encodes a novel protein kinase involved in
Ras-mediated signaling in C. elegans
. Cell 83: 903-913. (Abstract)

Kornfeld, K., K.-L. Guan and H.R. Horvitz. 1995. The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK. Genes & Development 9: 756-768. (Abstract)

Lackner, M.R., K. Kornfeld, L.M. Miller, H.R. Horvitz and S.K. Kim. 1994. A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans. Genes & Development 8: 160-173. (Abstract)

 

 


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This page last edited May 20, 2016
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